Article
Z-2 aldose reductase allele and diabetic retinopathy in India.
Ophthalmic genetics - 1 Mar 2003
Kumaramanickavel Govindasamy, Sripriya Sarangapani, Ramprasad Vedam Lakshmi, Upadyay Neelam Kumari, Paul Pradeep George, Sharma Tarun
Abstract excerpt
Genetic factors have been identified that regulate the severity and the rapidity of onset of retinopathy in diabetic patients. Polymorphisms in (CA)( n) present upstream of the promoter of the aldose reductase (ALR2 ) gene have been shown to be associated with retinopathy in different ethnic populations. We aimed to study the association between the (CA)( n) polymorphism and type 2 diabetic patients with and...
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