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The Relationship Between Aldose Reductase C106T Polymorphism and Diabetic Retinopathy: An Updated Meta-Analysis.

Investigative ophthalmology & visual science - 1 Apr 2015

Zhou Minwen, Zhang Pengfei, Xu Xun, Sun Xiaodong

Abstract excerpt

PURPOSE: Studies investigating the associations between aldose reductase (ALR) genetic polymorphisms and diabetic retinopathy (DR) have reported controversial results. Therefore, to shed light on these inconclusive findings, we performed this meta-analysis to clarify the effects of ALR C(-106)T polymorphism on DR risk. METHODS: Relevant studies were selected through an extensive search of PubMed, EMBASE, the Web...

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PMID: 25722213
DOI: 10.1167/iovs.14-16279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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