Article
Differential regulation of mesodermal gene expression by Drosophila cell type-specific Forkhead transcription factors.
Development (Cambridge, England) - 1 Apr 2012
Zhu Xianmin, Ahmad Shaad M, Aboukhalil Anton, Busser Brian W, Kim Yongsok, Tansey Terese R, Haimovich Adrian, Jeffries Neal, Bulyk Martha L, Michelson Alan M
Abstract excerpt
A common theme in developmental biology is the repeated use of the same gene in diverse spatial and temporal domains, a process that generally involves transcriptional regulation mediated by multiple separate enhancers, each with its own arrangement of transcription factor (TF)-binding sites and associated activities. Here, by contrast, we show that the expression of the Drosophila Nidogen (Ndg) gene at different...
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