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Article

Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of alpha1 glycine receptors.

Journal of neurochemistry - 1 Sept 2007

Crawford Daniel K, Trudell James R, Bertaccini Edward J, Li Kaixun, Davies Daryl L, Alkana Ronald L

Abstract excerpt

Considerable evidence indicates that ethanol acts on specific residues in the transmembrane domains of glycine receptors (GlyRs). In this study, we tested the hypothesis that the extracellular domain is also a target for ethanol action by investigating the effect of cysteine substitutions at positions 52 (extracellular domain) and 267 (transmembrane domain) on responses to n-alcohols and propyl...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17561937
DOI: 10.1111/j.1471-4159.2007.04680.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of alpha1 glycine receptors.PMID 17561937Read ↗

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