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Article

Synaptic P2X7 receptor regenerative-loop hypothesis for depression.

The Australian and New Zealand journal of psychiatry - 1 Jul 2007

Bennett Maxwell R

Abstract excerpt

Forty-five years ago the surprising discovery was made, in a Melbourne University laboratory, that peripheral synapses exist that release neither noradrenaline nor acetylcholine. The same laboratory went on to show that one of these then novel transmitters is adenosine 5'-triphosphate (ATP), for which a class of receptors has been dubbed P2X7. Recent linkage studies have shown that the P2X7 gene is associated...

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Identifiers

PMID: 17558618
DOI: 10.1080/00048670701399994

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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