Article

Understanding the genetic and molecular mechanisms of neurological diseases associated with cortical spreading depression : REST and P2X7 receptor

2018-01-01

Abstract excerpt

Cortical spreading depression (CSD) is a transient propagating wave of neuronal and glial excitation, followed by depression, which is implicated in migraine, traumatic brain injury (TBI) and stroke. Yet mechanisms of these diseases associated with CSD are not fully understood. The transcription factor, repressor element-1 silencing factor (REST), plays a critical role in the processes of central nervous system (C...

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Literature Corpus work: 64c8c2f5-dd90-521b-9ba5-f7422901212b
DOI: 10.17638/03022480

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