Article
The role of purinergic signaling in depressive disorders.
Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology - 1 Dec 2012
Sperlagh Beata, Csolle Cecilia, Ando Romeo D, Goloncser Flora, Kittel Agnes, Baranyi Maria
Abstract excerpt
The purinergic signaling system consists of transporters, enzymes and receptors responsible for the synthesis, release, action and extracellular inactivation of adenosine 5'-triphosphate (ATP) and its extracellular breakdown product adenosine. The actions of ATP are mediated ionotropic P2X and metabotropic P2Y receptor subfamilies, whilst the actions of adenosine are mediated by P1 adenosine receptors. Purinergic...
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