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Article

The biochemical, molecular, and genomic aspects of leukotriene C4 synthase.

Proceedings of the Association of American Physicians - 1 Jan 2000

Penrose J F, Austen K F

Abstract excerpt

Leukotriene C4 (LTC4) synthase is an 18 kD integral membrane enzyme of the 5-lipoxygenase/LTC4 synthase pathway and is positioned as the pivotal and only committed enzyme for the formation of the cysteinyl leukotrienes. Although its function is to conjugate catalytically LTA4 to reduced glutathione, LTC4 synthase is differentiated from other glutathione S-transferase family members by its lack of amino acid...

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Identifiers

PMID: 10591082
DOI: 10.1046/j.1525-1381.1999.99212.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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