Article
Mechanistic constraints on diversity in human V(D)J recombination.
Molecular and cellular biology - 1 Jan 1996
Gauss G H, Lieber M R
Abstract excerpt
We have analyzed a large collection of coding junctions generated in human cells. From this analysis, we infer the following about nucleotide processing at coding joints in human cells. First, the pattern of nucleotide loss from coding ends is influenced by the base composition of the coding end sequences. AT-rich sequences suffer greater loss than do GC-rich sequences. Second, inverted repeats can occur at ends...
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