Article
RAD marker microarrays enable rapid mapping of zebrafish mutations.
Genome biology - 1 Jan 2007
Miller Michael R, Atwood Tressa S, Eames B Frank, Eberhart Johann K, Yan Yi-Lin, Postlethwait John H, Johnson Eric A
Abstract excerpt
We constructed a restriction site associated DNA (RAD) marker microarray to facilitate rapid genetic mapping of zebrafish mutations. Using these microarrays with a bulk segregant approach, we localized previously unmapped mutations to genomic regions just a few centiMorgans in length. Furthermore, we developed an approach to assay individual RAD markers in pooled populations and refined one region. The RAD...
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