Article
A comparative map of the zebrafish genome.
Genome research - 1 Dec 2000
Woods I G, Kelly P D, Chu F, Ngo-Hazelett P, Yan Y L, Huang H, Postlethwait J H, Talbot W S
Abstract excerpt
Zebrafish mutations define the functions of hundreds of essential genes in the vertebrate genome. To accelerate the molecular analysis of zebrafish mutations and to facilitate comparisons among the genomes of zebrafish and other vertebrates, we used a homozygous diploid meiotic mapping panel to localize polymorphisms in 691 previously unmapped genes and expressed sequence tags (ESTs). Together with earlier...
Topics
- Animals
- Chromosome Mapping
- Conserved Sequence
- Databases, Factual
- Expressed Sequence Tags
- Gene Duplication
- Genetic Linkage
- Genome
- Humans
- Mutation
- Sequence Homology, Nucleic Acid