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Article

Rapid and cost-effective polymorphism identification and genotyping using restriction site associated DNA (RAD) markers.

Genome research - 1 Feb 2007

Miller Michael R, Dunham Joseph P, Amores Angel, Cresko William A, Johnson Eric A

Abstract excerpt

Restriction site associated DNA (RAD) tags are a genome-wide representation of every site of a particular restriction enzyme by short DNA tags. Most organisms segregate large numbers of DNA sequence polymorphisms that disrupt restriction sites, which allows RAD tags to serve as genetic markers spread at a high density throughout the genome. Here, we demonstrate the applicability of RAD markers for both individual...

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Identifiers

PMID: 17189378
DOI: 10.1101/gr.5681207
PMCID: PMC1781356

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