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<i>Clostridium difficile</i> toxin expression is inhibited by the novel regulator TcdC

30 May 2007

Abstract excerpt

Clostridium difficile, an emerging nosocomial pathogen of increasing clinical significance, produces two large protein toxins that are responsible for the cellular damage associated with the disease. The precise mechanisms by which toxin synthesis is regulated in response to environmental change have yet to be discovered. The toxin genes (tcdA and tcdB) are located in a pathogenicity locus (PaLoc), along with...

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PMID: 17542920
DOI: 10.1111/j.1365-2958.2007.05739.x

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