Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of the Pathogenicity Locus in<i>Clostridium difficile</i>Strains

1 Feb 2000

Abstract excerpt

The genes for Clostridium difficile toxins A and B (tcdA and tcdB) are part of a 19.6-kb pathogenicity locus (PaLoc) that includes the genes tcdD, tcdE, and tcdC. To determine whether the C. difficile PaLoc is a stable and conserved genetic unit in toxigenic strains, a multiplex polymerase chain reaction was used to analyze 50 toxigenic, 39 nontoxigenic, and 2 toxin-defective isolates. The respective amplicons...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Clostridium difficile and Clostridium perfringens research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10669352
DOI: 10.1086/315248

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of the Pathogenicity Locus in<i>Clostridium difficile</i>StrainsPMID 10669352Read ↗

Clostridium difficile: New Insights into the Evolution of the Pathogenicity LocusSemantic proximity Read ↗

Molecular characterization of pathogenicity locus (PaLoc) and tcdC genetic diversity among tcdA+B+Clostridioides difficile clinical isolates in Tehran, Iran.Semantic proximity Read ↗

Molecular Characterization of Pathogenicity Locus (PaLoc) and tcdC Genetic Diversity Among tcdA+B+ Clostridioides Difficile Clinical Isolates in Tehran, IranSemantic proximity Read ↗

Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elementsSemantic proximity Read ↗

Molecular analysis of the pathogenicity locus and polymorphism in the putative negative regulator of toxin production (TcdC) among Clostridium difficile clinical isolates.Semantic proximity Read ↗

The Complexity and Diversity of the Pathogenicity Locus in Clostridium difficile Clade 5Semantic proximity Read ↗

Transcription Analysis of the Genes <i>tcdA‐E</i> of the Pathogenicity Locus of <i>Clostridium Difficile</i>Semantic proximity Read ↗

Heterogeneity of large clostridial toxins: importance of<i>Clostridium difficile</i>toxinotypesSemantic proximity Read ↗

CdtR Regulates TcdA and TcdB Production in Clostridium difficileSemantic proximity Read ↗

Comparative genomics of Clostridioides difficile toxinotypes identifies module-based toxin gene evolutionSemantic proximity Read ↗

Genomic and phenotypic studies among <i>Clostridioides difficile</i> isolates show a high prevalence of clade 2 and great diversity in clinical isolates from Mexican adults and children with healthcare-associated diarrheaSemantic proximity Read ↗

<i>Clostridium difficile</i> toxin expression is inhibited by the novel regulator TcdCSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.