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Article

Na(+)-induced inward rectification in the two-pore domain K(+) channel, TASK-2.

American journal of physiology. Renal physiology - 1 Jan 2005

Morton Michael J, Chipperfield Sarah, Abohamed Abdulrahman, Sivaprasadarao Asipu, Hunter Malcolm

Abstract excerpt

TASK-2 is a member of the two-pore domain K(+) (K(2P)) channel family that is expressed at high levels in several epithelia, including the proximal tubule. In common with the other TASK channels, TASK-2 is sensitive to changes in extracellular pH. We have expressed human TASK-2 in Chinese hamster ovary cells and studied whole cell and single-channel activity by patch clamp. The open probability of K(2P) channels...

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Source

Identifiers

PMID: 15328068
DOI: 10.1152/ajprenal.00248.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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