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Article

The genetic control of susceptibility to Mycobacterium tuberculosis.

Novartis Foundation symposium - 1 Jan 2007

Britton W J, Fernando S L, Saunders B M, Sluyter R, Wiley J S

Abstract excerpt

Mycobacterium tuberculosis is one of the most successful human pathogens, surviv ing in latent foci of infection in one third of humanity, yet causing lung necrosis in sufficient individuals to ensure its transmission. Each stage of the host response to M. tuberculosis is under genetic control, including the initial encounter with mycobacteria by macrophages, epithelial cells and dendritic cells in the lung,...

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Share to Genetic Predisposition to Disease
Share to Macrophages
Share to Mycobacterium tuberculosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Receptors, Purinergic P2

Share to Receptors, Purinergic P2X7

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Source

Identifiers

PMID: 17534067
DOI: 10.1002/9780470062128.ch8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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