Article

P2X7 Gene Polymorphisms and Risk Assessment for Pulmonary Tuberculosis in Asian Indians

2010-01-01

Abstract excerpt

Objective: Pulmonary tuberculosis (PTB) is a leading cause of morbidity and mortality. Macrophages play an important role in the immunopathogenesis of tuberculosis. Extracellular ATP induces macrophage bactericidal activity through activation of the purinergic P2X7 receptor. This case- control study assesses the association of −762 T/C, 1513A/C and 1729T/A P2X7 polymorphisms in patients with PTB and healthy contro...

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Literature Corpus work: e80669a2-ded7-585e-b1c7-c442a904af1d
DOI: 10.1155/2010/843729

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