Article
Genetic susceptibility in tuberculosis.
Respirology (Carlton, Vic.) - 1 Feb 2010
Yim Jae-Joon, Selvaraj Paramasivam
Abstract excerpt
The importance of host genetic factors in determining susceptibility to tuberculosis (TB) has been studied extensively using various methods, such as case-control, candidate gene and genome-wide linkage studies. Several important candidate genes like human leucocyte antigen/alleles and non-human leucocyte antigen genes, such as cytokines and their receptors, chemokines and their receptors, pattern recognition...
Topics
- Chemokines
- Cytokines
- Genetic Predisposition to Disease
- HLA-DR2 Antigen
- Humans
- Receptors, Purinergic P2
- Receptors, Purinergic P2X7
- Toll-Like Receptors
- Tuberculosis