Article
P2X7 receptor in spinal tuberculosis: Gene polymorphisms and protein levels in Chinese Han population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2018
Zhou Ying, Tan Chun-Yan, Mo Zhi-Jiang, Gao Qi-le, He Dan, Li Jiong, Huang Rong-Fu, Li Yan-Bing, Guo Chao-Feng, Guo Qiang, Wang Long-Jie, Yang Guan-Teng, Zhang Hong-Qi
Abstract excerpt
Spinal tuberculosis (TB) accounts for 1%-5% of all TB infections. Host genetic variation influences susceptibility to Mycobacterium tuberculosis (MTB). P2X7 receptor (P2X7R) expressed on cells has been identified as a regulatory molecule in cell death/apoptosis, killing of intercellular pathogens, and bone turnover. This study investigated the P2X7 gene polymorphisms and protein levels in spinal TB. P2X7 gene...
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