Article
P2X7 gene polymorphisms and risk assessment for pulmonary tuberculosis in Asian Indians.
Disease markers - 1 Jan 2010
Sambasivan Venkatasubramanian, Murthy Kolluri Janaki Rama, Reddy Ravindra, Vijayalakshimi Valluri, Hasan Qurratulain
Abstract excerpt
OBJECTIVE: Pulmonary tuberculosis (PTB) is a leading cause of morbidity and mortality. Macrophages play an important role in the immunopathogenesis of tuberculosis. Extracellular ATP induces macrophage bactericidal activity through activation of the purinergic P2X7 receptor. This case- control st...
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