Structural correlates of COMT Val158Met polymorphism in childhood ADHD: a voxel-based morphometry study.

doi:10.3109/15622975.2014.984629

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Structural correlates of COMT Val158Met polymorphism in childhood ADHD: a voxel-based morphometry study.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Apr 2015

Villemonteix Thomas, De Brito Stéphane A, Slama Hichem, Kavec Martin, Balériaux Danielle, Metens Thierry, Baijot Simon, Mary Alison, Ramoz Nicolas, Septier Mathilde, Gorwood Philip, Peigneux Philippe, Massat Isabelle

Abstract excerpt

OBJECTIVES: The Val158-allele of the catechol-O-methyltransferase (COMT) Val158Met (rs4680) functional polymorphism has been identified as a risk factor for antisocial behaviour in attention-deficit/hyperactivity disorder (ADHD). Here, we used voxel-based morphometry to investigate the effects of Val158Met polymorphism on grey matter (GM) volumes in a sample of 7-13-year-old children. METHODS: MRI and genotype...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antisocial Personality Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Attention Deficit Disorder with Hyperactivity

Share to Catechol O-Methyltransferase

Share to Caudate Nucleus

Share to Gray Matter

Share to Magnetic Resonance Imaging

Share to Prefrontal Cortex

Share to Temporal Lobe

Source

Open in PubMed

Identifiers

PMID: 25495556
DOI: 10.3109/15622975.2014.984629

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural correlates of COMT Val158Met polymorphism in childhood ADHD: a voxel-based morphometry study.PMID 25495556Read ↗

Genetic Variation in the Catechol-O-Methyl Transferase Val108/158Met Is Linked to the Caudate and Posterior Cingulate Cortex Volume in Healthy Subjects: Voxel-Based Morphometry Analysis of Brain Magnetic Resonance Imaging.Semantic proximity Read ↗

Met158 variant of the catechol-O-methyltransferase genotype is associated with thicker cortex in adult brain.Semantic proximity Read ↗

Impact of catechol-O-methyltransferase Val(108/158) Met genotype on hippocampal and prefrontal gray matter volume.Semantic proximity Read ↗

The COMT val158met polymorphism and brain morphometry in healthy young adults.Semantic proximity Read ↗

The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults.Semantic proximity Read ↗

Catechol-O-methyltransferase polymorphism is associated with the cortico-cerebellar functional connectivity of executive function in children with attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

Effects of COMT polymorphisms on brain function and behavior in health and disease.Semantic proximity Read ↗

Associations between serotonin transporter gene (SLC6A4) methylation and clinical characteristics and cortical thickness in children with ADHD.Semantic proximity Read ↗

Relationship between the catechol-O-methyl transferase Val108/158Met genotype and brain volume in treatment-naive major depressive disorder: Voxel-based morphometry analysis.Semantic proximity Read ↗

Attention-deficit/hyperactivity disorder phenotype is influenced by a functional catechol-O-methyltransferase variant.Semantic proximity Read ↗

COMT genotype affects brain white matter pathways in attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

Gray matter volumetric correlates of attention deficit and hyperactivity traits in emerging adolescentsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.