Article
Sexually divergent effect of COMT Val/met genotype on subcortical volumes in schizophrenia.
Brain imaging and behavior - 1 Jun 2018
Bollettini Irene, Spangaro Marco, Poletti Sara, Lorenzi Cristina, Pirovano Adele, Vai Benedetta, Smeraldi Enrico, Cavallaro Roberto, Benedetti Francesco
Abstract excerpt
Structural and functional alterations of subcortical areas have been observed in schizophrenia. COMT Val108/158Met has been associated with schizophrenia and implicated in different cognitive and neurofunctional alterations. Recent studies suggested that COMT genotype influences neuronal growth. Genetic variations in COMT were associated with sexually dimorphic effects on enzymatic activity, brain anatomy and...
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