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Article

COMT val158Met and executive control: a test of the benefit of specific deficits to translational research.

Journal of abnormal psychology - 1 May 2007

MacDonald Angus W, Carter Cameron S, Flory Janine D, Ferrell Robert E, Manuck Stephen B

Abstract excerpt

The role of catechol-O-methyltransferase (COMT) val158met in prefrontal cortical deficits associated with the liability to schizophrenia remains controversial. This study evaluated 464 healthy adult participants using three measures of executive functions in working memory: a 3-back version of th...

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Source

Identifiers

PMID: 17516763
DOI: 10.1037/0021-843X.116.2.306

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17516763-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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COMT val158Met and executive control: a test of the benefit of specific deficits to translational research.PMID 17516763Read ↗

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Catechol-O-methyltransferase polymorphisms and some implications for cognitive therapeutics.Semantic proximity Read ↗

Differential effects of the catechol-O-methyltransferase Val158Met genotype on the cognitive function of schizophrenia patients and healthy Japanese individuals.Semantic proximity Read ↗

Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls.Semantic proximity Read ↗

Executive attention in schizophrenic males and the impact of COMT Val108/158Met genotype on performance on the attention network test.Semantic proximity Read ↗

Effects of the catechol-O-methyltransferase Val158Met polymorphism on executive function: a meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controls.Semantic proximity Read ↗

Catechol-O-methyltransferase (COMT) genotypes and working memory: associations with differing cognitive operations.Semantic proximity Read ↗

Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia.Semantic proximity Read ↗

COMT, neuropsychological function and brain structure in schizophrenia: a systematic review and neurobiological interpretation.Semantic proximity Read ↗

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