Article
Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis.
The Journal of clinical endocrinology and metabolism - 1 Aug 2007
Kavvoura Fotini K, Akamizu Takashi, Awata Takuya, Ban Yoshiyuki, Chistiakov Dimitry A, Frydecka Irena, Ghaderi Abbas, Gough Stephen C, Hiromatsu Yuji, Ploski Rafal, Wang Pei-Wen, Ban Yoshio, Bednarczuk Tomasz, Chistiakova Emma I, Chojm Marcin, Heward Joanne M, Hiratani Hitomi, Juo Suh-Hang Hank, Karabon Lidia, Katayama Shigehiro, Kurihara Susumu, Liu Rue-Tsuan, Miyake Ikuyo, Omrani Gholam-Hossein R, Pawlak Edyta, Taniyama Matsuo, Tozaki Teruaki, Ioannidis John P A
Abstract excerpt
CONTEXT: Cytotoxic T-lymphocyte associated antigen 4 (CTLA-4) polymorphisms have been widely examined for their associations with autoimmune thyroid diseases [Graves' disease (GD) and Hashimoto thyroiditis (HT)], but their relative population effect remains unclear. OBJECTIVE: The aim was to generate large-scale evidence on whether the CTLA-4 polymorphisms (A49G and CT60) and haplotypes thereof increase the...
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