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Article

Association of CT60 polymorphism of the CTLA4 gene with Graves' disease in Taiwanese children.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Jul 2008

Tsai Suei-Tsau, Huang Chi-Yu, Lo Fu-Sung, Chang Ya-Ting, Tanizawa Takakuni, Chen Chi-Kai, Wang Zen-Chong, Liu Hsin-Fu, Chu Chen-Chung, Lin Marie, Lin Chao-Hsu, Li Hsin-Jung, Lee Yann-Jinn

Abstract excerpt

BACKGROUND: The CTLA4 gene is involved in the activity of T cells. AIM: To determine the association between Graves' disease (GD) susceptibility and CT60 polymorphism of the CTLA4 gene. PATIENTS: 189 children with GD and 620 healthy controls. METHODS: We determined the genotype with restriction fragment length polymorphism and compared results. RESULTS: Genotype G/G was significantly associated with GD (odds...

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Source

Identifiers

PMID: 18780601
DOI: 10.1515/jpem.2008.21.7.665

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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