Article
Associations Between Three CTLA-4 Polymorphisms and Hashimoto's Thyroiditis Risk: An Updated Meta-Analysis with Trial Sequential Analysis.
Genetic testing and molecular biomarkers - 1 Apr 2018
Hu Yifang, Xu Kuanfeng, Jiang Lin, Zhang Lijuan, Shi He, Cui Dai
Abstract excerpt
AIMS: In this article, we conducted an updated meta-analysis with trial sequential analysis (TSA) to refine the associations between three common single nucleotide polymorphisms (SNPs) in the CTLA-4 gene (+49A/G, CT60, and -318C/T) and Hashimoto's thyroiditis (HT). METHODS: Statistical association analyses were performed using four genetic models, including the allelic, codominant, dominant, and recessive models...
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