Article
Association of genetic polymorphisms in CASP7 with risk of ischaemic stroke.
Scientific reports - 9 Dec 2019
Zheng Zhaoshi, Liu Songyan, Wang Chuheng, Wang Chunhui, Tang Dong, Shi Yuqing, Han Xuemei
Abstract excerpt
Caspase 7 (CASP7) is located on chromosome 10q25.3 that has been identified to be a susceptibility locus of ischaemic stroke (IS) by genome-wide association study. Elevated CASP7 was observed in IS, acting as a key apoptotic mediator in the development of IS. The aim of this study was to investigate the association between genetic polymorphisms in CASP7 and risk of IS. The CASP7 polymorphisms were genotyped using...
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