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Article

NPSR1 gene is associated with reduced risk of rheumatoid arthritis.

The Journal of rheumatology - 1 Jun 2012

Robledo Gema, González-Gay Miguel Angel, Fernández-Gutiérrez Benjamín, Lamas José Ramón, Balsa Alejandro, Pascual-Salcedo Dora, Castañeda Santos, Blanco Ricardo, González-Alvaro Isidoro, García Antonio, Raya Enrique, Gómez-Vaquero Carmen, Delgado Mario, Martín Javier

Abstract excerpt

OBJECTIVE: Neuropeptide S receptor 1 (NPSR1) is a G protein-coupled receptor involved in immune response and is associated with several inflammatory diseases. We investigated the possible contribution of several polymorphisms in the intronic region of NPSR1 to rheumatoid arthritis (RA). METHODS: Genotyping of 7 single-nucleotide polymorphisms (SNP) was performed in a total of 1232 patients with RA and 983 healthy...

Read the complete abstract on PubMed

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Share to Arthritis, Rheumatoid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

Share to Receptors, G-Protein-Coupled

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Source

Identifiers

PMID: 22548958
DOI: 10.3899/jrheum.111205

Genes

NPSR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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