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Article

Association between genetic polymorphisms in the human interleukin-7 receptor alpha-chain and inhalation allergy.

International journal of immunogenetics - 1 Jun 2007

Shamim Z, Müller K, Svejgaard A, Poulsen L K, Bodtger U, Ryder L P

Abstract excerpt

Thymic stromal-derived lymphopoietin (TSLP) and interleukin-7 share a common receptor chain, IL-7Ralpha. IL-7 is involved in T-cell homeostasis, and TSLP induces production of pro-allergic cytokines. The gene encoding the IL-7Ralpha chain is polymorphic, and investigation of inhalation allergic patients compared with controls showed significant association with two alleles at position +1237 and +2087.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17504502
DOI: 10.1111/j.1744-313X.2007.00657.x

Genes

TSLP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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