Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms in the genes encoding human interleukin-7 receptor-alpha: prognostic significance in allogeneic stem cell transplantation.

Bone marrow transplantation - 1 Mar 2006

Shamim Z, Ryder L P, Heilmann C, Madsen H, Lauersen H, Andersen P K, Svejgaard A, Jacobsen N, Müller K

Abstract excerpt

Interleukin-7 (IL-7) is essential for T-cell development in the thymus and for the maintenance of peripheral T cells. IL-7 signals through IL-7R, that consists of the gammac-chain and an alpha-chain. Sequencing of IL-7Ralpha has revealed the existence of four single nucleotide polymorphisms (SNPs) (+510C/T, +1237 A/G, 2087T/C and +3110A/G), which all give rise to amino-acid substitutions. The aim of the present...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease-Free Survival
Share to Hematopoietic Stem Cell Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Prognosis

Share to Receptors, Interleukin-7

Share to Recurrence

Share to Survival Rate

Share to Tissue Donors

Share to Transplantation, Homologous

Source

Identifiers

PMID: 16435014
DOI: 10.1038/sj.bmt.1705277

Genes

SCT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms in the genes encoding human interleukin-7 receptor-alpha: prognostic significance in allogeneic stem cell transplantation.PMID 16435014Read ↗

Interleukin-7 receptor-alpha gene polymorphisms in bone marrow transplant recipients.Semantic proximity Read ↗

Prognostic significance of interleukin-7 receptor-α gene polymorphisms in allogeneic stem-cell transplantation: a confirmatory study.Semantic proximity Read ↗

Donor Genotype in the Interleukin-7 Receptor α-Chain Predicts Risk of Graft-versus-Host Disease and Cytomegalovirus Infection after Allogeneic Hematopoietic Stem Cell Transplantation.Semantic proximity Read ↗

Polymorphism in the interleukin-7 receptor-alpha and outcome after allogeneic hematopoietic cell transplantation with matched unrelated donor.Semantic proximity Read ↗

Soluble Interleukin-7 receptor levels and risk of acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation.Semantic proximity Read ↗

Association between genetic polymorphisms in the human interleukin-7 receptor alpha-chain and inhalation allergy.Semantic proximity Read ↗

Interleukin-7 receptor alpha (IL-7Ralpha) deficiency: cellular and molecular bases. Analysis of clinical, immunological, and molecular features in 16 novel patients.Semantic proximity Read ↗

The human IL-7 receptor gene: deletions, polymorphisms and mutations.Semantic proximity Read ↗

A pilot study of single nucleotide polymorphisms in the interleukin-6 receptor and their effects on pre- and post-transplant serum mediator level and outcome after allogeneic stem cell transplantation.Semantic proximity Read ↗

Deleterious and Oncogenic Mutations in the IL7RASemantic proximity Read ↗

Novel Synonymous Variant in IL7R Causes Preferential Expression of the Soluble Isoform.Semantic proximity Read ↗

Diagnosis and Treatment of a Patient With Severe Combined Immunodeficiency Due to a Novel Homozygous Mutation in the IL-7Rα Chain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.