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Article

Atopy and the human IL-4 receptor alpha chain.

The Journal of allergy and clinical immunology - 1 Jul 2000

Izuhara K, Yanagihara Y, Hamasaki N, Shirakawa T, Hopkin J M

Abstract excerpt

BACKGROUND: Atopy is a common inherited disorder characterized by increased IgE responsiveness, but no functional analysis of the candidate genes related to atopy has been performed. IL-4 is important for B-cell production of IgE, and the human IL-4 receptor alpha chain (hIL-4Ralpha) is crucial for the binding and signal transduction of IL-4, so hIL-4Ralpha may be a candidate gene related to atopy. OBJECTIVE: We...

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Source

Identifiers

PMID: 10887336
DOI: 10.1067/mai.2000.106776

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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