Association between the IL-7Rα gene polymorphisms of rs6897932 and rs987106 with atopic diseases: A case-control design

Abstract excerpt

<h4>Background: </h4> Atopy is used to describe the genetic tendency to IgE-mediated responses. Many factors contribute to predisposing individuals to atopy, including cytokines. IL-7 is a cytokine that mediates hypersensitivity responses and proliferation of T cells and has a polymorphic gene for its receptor (CD127). These different alleles may affect the signaling cascade or alter the production of inflammatory...

Topics

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• Asthma
• Case-Control Studies
• Denmark
• Gene Frequency
• Genetic Predisposition to Disease
• Polymorphism, Single Nucleotide
• Receptors, Interleukin-7
• Respiratory Hypersensitivity

Identifiers and source

Literature Corpus work

cfec2b08-da8d-588b-a7ab-b634f4faa589

DOI

10.21203/rs.3.rs-1330371/v1