Article
Genetic variations of SOCS1 are associated with chronic hepatitis B virus infection.
Human immunology - 1 Aug 2014
Zhang Pingping, Li Fang, Li Na, Zhu Qianqian, Yang Cuiling, Han Qunying, Chen Jinghong, Lv Yi, Yu Ling, Wei Ping, Liu Zhengwen
Abstract excerpt
Suppressor of cytokine signaling (SOCS)-1 is involved in viral infection through regulation of both innate and adaptive immunity. The SOCS1 gene polymorphisms may affect the outcome of viral infection. The relationship between SOCS1 polymorphisms and hepatitis B virus (HBV) infection has not yet been explored. This study genotyped SOCS1 rs243327 and rs33932899 polymorphisms in 477 patients with chronic HBV...
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