Article
Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles.
Journal of virology - 1 Jul 2007
Streeck Hendrik, Lichterfeld Mathias, Alter Galit, Meier Angela, Teigen Nickolas, Yassine-Diab Bader, Sidhu Harlyn K, Little Susan, Kelleher Anthony, Routy Jean-Pierre, Rosenberg Eric S, Sekaly Rafick-Pierre, Walker Bruce D, Altfeld Marcus
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1)-specific immune responses during primary HIV-1 infection appear to play a critical role in determining the ultimate speed of disease progression, but little is known about the specificity of the initial HIV-1-specific CD8(+) T-cell responses in individuals expressing protective HLA class I alleles. Here we compared HIV-1-specific T-cell responses between subjects...
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