Article
Characterization of HLA-B57-restricted human immunodeficiency virus type 1 Gag- and RT-specific cytotoxic T lymphocyte responses.
The Journal of general virology - 1 Sept 1998
Klein M R, van der Burg S H, Hovenkamp E, Holwerda A M, Drijfhout J W, Melief C J, Miedema F
Abstract excerpt
HLA-B57 has been shown to be strongly associated with slow disease progression in human immunodeficiency virus type 1 (HIV-1)-infected patients from the Amsterdam Cohort. Since HIV-1-specific CTL can control and eliminate virus-infected cells, we sought to characterize the dominant HLA-B57-restri...
Topics
- Alleles
- Amino Acid Sequence
- Case-Control Studies
- Cohort Studies
- Gene Products, gag
- Genetic Variation
- HIV Antigens
- HIV Infections
- HIV Reverse Transcriptase
- HIV-1
- HLA-B Antigens
- Humans
- Immunodominant Epitopes
- In Vitro Techniques
- Longitudinal Studies
- Male
- Netherlands
- Survivors