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DNA double-strand break repair capacity and risk of breast cancer.

Carcinogenesis - 1 Aug 2007

Bau Da-Tian, Mau Yi-Chien, Ding Shian-Ling, Wu Pei-Ei, Shen Chen-Yang

Abstract excerpt

A tumorigenic role of the non-homologous end-joining (NHEJ) pathway for the repair of DNA double-strand breaks (DSBs) has been suggested by our finding of a significant association between increased breast cancer risk and a cooperative effect of single-nucleotide polymorphisms in NHEJ genes. To confirm this finding, this case-control study detected both in vivo and in vitro DNA end-joining (EJ) capacities in...

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Identifiers

PMID: 17494053
DOI: 10.1093/carcin/bgm109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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