Article
DNA double-strand break repair capacity and risk of breast cancer.
Carcinogenesis - 1 Aug 2007
Bau Da-Tian, Mau Yi-Chien, Ding Shian-Ling, Wu Pei-Ei, Shen Chen-Yang
Abstract excerpt
A tumorigenic role of the non-homologous end-joining (NHEJ) pathway for the repair of DNA double-strand breaks (DSBs) has been suggested by our finding of a significant association between increased breast cancer risk and a cooperative effect of single-nucleotide polymorphisms in NHEJ genes. To c...
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