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Article

Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: a multigenic study on cancer susceptibility.

Cancer research - 15 May 2003

Fu Yi-Ping, Yu Jyh-Cherng, Cheng Ting-Chih, Lou M Ann, Hsu Giu-Cheng, Wu Chia-Yun, Chen Sou-Tong, Wu Hurng-Sheng, Wu Pei-Ei, Shen Chen-Yang

Abstract excerpt

The role of the familial breast cancer susceptibility genes, BRCA1 and BRCA2, in the homologous recombination pathway for DNA double-strand break (DSB) repair suggests that the mechanisms involved in DNA DSB repair are of particular etiological importance during breast tumorigenesis. However, there is currently no evidence for an association between breast cancer and the other DSB repair pathway, the...

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Identifiers

PMID: 12750264

Genes

XRCC4
BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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