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Article

Association between XRCC5, 6 and 7 gene polymorphisms and the risk of breast cancer: a HuGE review and meta-analysis.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Zhou Li-Ping, Luan Hong, Dong Xi-Hua, Jin Guo-Jiang, Man Dong-Liang, Shang Hong

Abstract excerpt

OBJECTIVE: Non-homologous end joining (NHEJ) is a pathway for repairing DNA double-strand breaks. Recent publications indicated that XRCC5, XRCC6 and XRCC7 genes may participate in the pathogenesis of breast cancer. The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis was to investigate associations between XRCC5, XRCC6 and XRCC7 genetic polymorphisms in the NHEJ pathway and breast cancer...

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Identifiers

PMID: 23098447
DOI: 10.7314/apjcp.2012.13.8.3637

Genes

XRCC5
XRCC6

Provenance

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