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Article

Characterization of three novel mechanosensitive channel activities in Escherichia coli.

Channels (Austin, Tex.) - 1 Jan 2000

Edwards Michelle D, Black Susan, Rasmussen Tim, Rasmussen Akiko, Stokes Neil R, Stephen Terri-Leigh, Miller Samantha, Booth Ian R

Abstract excerpt

Mechanosensitive channels sense elevated membrane tension that arises from rapid water influx occurring when cells move from high to low osmolarity environments (hypoosmotic shock). These non-specific channels in the cytoplasmic membrane release osmotically-active solutes and ions. The two major mechanosensitive channels in Escherichia coli are MscL and MscS. Deletion of both proteins severely compromises...

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Identifiers

PMID: 22874652
DOI: 10.4161/chan.20998
PMCID: PMC3508906

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of three novel mechanosensitive channel activities in Escherichia coli.PMID 22874652Read ↗

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