Article
Linkage of Graves' disease to the human leucocyte antigen region in the Chinese-Han population in Taiwan.
Clinical endocrinology - 1 May 2007
Chen Pei-Lung, Fann Cathy Shen-Jang, Chang Chien-Ching, Wu I-Lin, Chiu Wei-Yih, Lin Chin-Yu, Yang Wei-Shiung, Chang Tien-Chun
Abstract excerpt
OBJECTIVE: To investigate whether markers in the candidate chromosome regions, including the human leucocyte antigen (HLA) region, are linked to Graves' disease (GD). DESIGN: A familial linkage study with a candidate region approach. PATIENTS: A total of 536 individuals in 122 multiplex Chinese-Han families with a GD proband and at least one other affected sibling, resulting in 270 affected sib-pairs. Subjects...
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