Article
Human leucocyte antigen alleles confer susceptibility and progression to Graves' ophthalmopathy in a Southern Chinese population.
The British journal of ophthalmology - 1 Oct 2021
Huang Xiaosheng, Liu Guiqin, Mei Shaoyi, Cai Jiamin, Rao Jing, Tang Minzhong, Zhu Tianhui, Chen Wenchiew, Peng Shiming, Wang Yan, Ye Ye, Zhang Tong, Deng Zhihui, Zhao Jun
Abstract excerpt
PURPOSE: To evaluate the contributions of human leucocyte antigen (HLA) class I and II genes in the development of Graves' ophthalmopathy (GO) in a Southern Chinese population. METHODS: Eight HLA loci were genotyped and analysed in 272 unrelated patients with Graves' disease (GD) or the proptosis and myogenic phenotypes of GO, and 411 ethnically matched control subjects. RESULTS: The allele frequencies of...
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