Article
[A linkage study of cytotoxic T lymphocyte-associated antigen 4 gene and Graves' disease in northern Chinese Han ethnic].
Zhonghua nei ke za zhi - 1 Dec 2002
Jin Ying, Ben Songtao, Teng Weiping, Zhang Jing, Xiong Xiaoyan, Zhao Yu, Huang Wei
Abstract excerpt
OBJECTIVE: To determine if the cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) gene, which is located on chromosome 2q31-q33, is the major susceptibility gene for Graves' disease (GD) of northern Chinese Han nationality. METHODS: Five highly polymorphic microsatellite markers spanning the entire region of chromosome 2q31-q33 were employed to screen 54 families with multiple incidences of GD (322 individuals)...
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