Article
[The human major histocompatibility complex region is not a major susceptibility locus for Graves disease among the Hans in north of China].
Zhonghua yi xue za zhi - 25 Sept 2002
Jin Ying, Hu Fengnan, Teng Weiping, Ben Songtao, Zhang Jing, Xiong Xiaoyan, Huang Wei
Abstract excerpt
OBJECTIVE: To determine if the human major histocompatibility complex (MHC) region located on chromosome 6 p21 is a major susceptibility locus for Graves' disease (GD) among the Hans in North of China. METHODS: Four highly polymorphic microsatellite markers spanning the entire region of chromosome 6 p21 were employed to screen the DNA from blood samples of 54 Han multiplex families with GD (322 individuals) in...
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