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Article

Age and Sex of Mice Markedly Affect Survival Times Associated with Hyperoxic Acute Lung Injury.

PloS one - 1 Jan 2015

Prows Daniel R, Gibbons William J, Smith Jessica J, Pilipenko Valentina, Martin Lisa J

Abstract excerpt

Mortality associated with acute lung injury (ALI) remains substantial, with recent estimates of 35-45% similar to those obtained decades ago. Although evidence for sex-related differences in ALI mortality remains equivocal, death rates differ markedly for age, with more than 3-fold increased mortality in older versus younger patients. Strains of mice also show large differences in ALI mortality. To tease out...

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Identifiers

PMID: 26103466
DOI: 10.1371/journal.pone.0130936
PMCID: PMC4478006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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