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Article

Cytotoxic T-lymphocyte associated antigen-4 gene polymorphisms and primary biliary cirrhosis: a systematic review.

Journal of gastroenterology and hepatology - 1 Jul 2012

Li Man, Zheng Hao, Li Tao, Gao Ping, Zhang Xiao-Lin, Liu Dian-Wu

Abstract excerpt

BACKGROUND AND AIM: The cytotoxic T-lymphocyte antigen 4 (CTLA4) is an inhibitory receptor expressed on activated and regulatory T lymphocytes. Polymorphisms could have remarkable effects on susceptibility to autoimmunity. However, the associations between CTLA-4 polymorphisms and primary biliary cirrhosis (PBC) remain ambiguous. The aim of this meta-analysis is to determine more precise estimations of the...

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Share to CTLA-4 Antigen
Share to CTLA4 gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Liver Cirrhosis, Biliary

Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 22414241
DOI: 10.1111/j.1440-1746.2012.07118.x

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cytotoxic T-lymphocyte associated antigen-4 gene polymorphisms and primary biliary cirrhosis: a systematic review.PMID 22414241Read ↗

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