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Article

Association between TP53 codon 72 single-nucleotide polymorphism and radiation sensitivity of human fibroblasts.

Radiation research - 1 May 2007

Alsbeih G, Al-Harbi N, Al-Buhairi M, Al-Hadyan K, Al-Hamed M

Abstract excerpt

Inherent radiosensitivity varies widely between individuals. We hypothesized that amino acid substitution variants in two highly radiation-responsive proteins, TP53 (p53) and CDKN1A (p21, Waf1, Cip1), are associated with and could explain individual variations in radiosensitivity. The two non-synonymous single-nucleotide polymorphisms (SNPs) TP53 codon 72 Arg/Pro G>C and CDKN1A codon 31 Ser/Arg C>A were genotyped...

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Identifiers

PMID: 17474797
DOI: 10.1667/RR0830.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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