Article
Gender bias in individual radiosensitivity and the association with genetic polymorphic variations.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 May 2016
Alsbeih Ghazi, Al-Meer Rafa S, Al-Harbi Najla, Bin Judia Sara, Al-Buhairi Muneera, Venturina Nikki Q, Moftah Belal
Abstract excerpt
PURPOSE: To assess the extent of variation in radiosensitivity between individuals, gender-related dissimilarity and impact on the association with single nucleotide polymorphisms (SNPs). MATERIALS AND METHODS: Survival curves of 152 fibroblast cell strains derived from both gender were generated. Individual radiosensitivity was characterized by the surviving fraction at 2Gy (SF2). SNPs in 10 radiation responsive...
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