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Article

Association between HSPA5 Promoter Polymorphisms and a Reduced Risk of Normal Tension Glaucoma.

Ophthalmic research - 1 Jan 2022

Lee Chia Chi, Wang Tzu Chen, Wang Hsin Yu, Hsu Bin, Shih Rong Jhen, Lo Neng Wen, Wang Chun Yuan

Abstract excerpt

INTRODUCTION: In normal tension glaucoma (NTG), factors other than elevated intraocular pressure (IOP) are likely to play a role in the pathogenesis of optic neuropathy. The potential similarities between Alzheimer's disease (AD) and NTG in cellular apoptosis leading to neurodegeneration have been shown in recent studies. Heat Shock Protein family A member 5 (HSPA5) promoter polymorphisms have been reported to be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35378534
DOI: 10.1159/000524173

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