Article
Evaluation of the IL1 Gene Cluster Single Nucleotide Polymorphisms in Primary Open-Angle Glaucoma Pathogenesis.
Genetic testing and molecular biomarkers - 1 Oct 2016
Mookherjee Suddhasil, Banerjee Deblina, Chakraborty Subhadip, Mukhopadhyay Indranil, Sen Abhijit, Ray Kunal
Abstract excerpt
AIMS: Dysregulation of the immune system has previously been implicated in glaucoma pathogenesis. In this study, we investigated the potential association of SNPs in the IL1 gene cluster, consisting of nine genes, with primary open-angle glaucoma (POAG) cases. These cases presented with low to normal intraocular pressures (<20 mmHg), and are referred to as non-high tension glaucoma (non-HTG) cases. MATERIALS AND...
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