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Article

Small nucleolar RNAs direct site-specific synthesis of pseudouridine in ribosomal RNA.

Cell - 16 May 1997

Ni J, Tien A L, Fournier M J

Abstract excerpt

Ten ACA yeast small nucleolar RNAs (snoRNAs) were shown to be required for site-specific synthesis of pseudouridine psi in ribosomal RNA. A common secondary folding motif for the snoRNAs and rRNA target segments predicts that site selection involves: (1) base pairing of the snoRNA with complementary rRNA elements flanking the site of modification, and (2) identification of a uridine located at a near-constant...

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PMID: 9160748
DOI: 10.1016/s0092-8674(00)80238-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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