Article
Small nucleolar RNAs direct site-specific synthesis of pseudouridine in ribosomal RNA.
Cell - 16 May 1997
Ni J, Tien A L, Fournier M J
Abstract excerpt
Ten ACA yeast small nucleolar RNAs (snoRNAs) were shown to be required for site-specific synthesis of pseudouridine psi in ribosomal RNA. A common secondary folding motif for the snoRNAs and rRNA target segments predicts that site selection involves: (1) base pairing of the snoRNA with complement...
Topics
- Animals
- Base Sequence
- Cell Nucleolus
- Chick Embryo
- Models, Biological
- Molecular Sequence Data
- Molecular Structure
- Mutation
- Nucleic Acid Conformation
- Pseudouridine
- RNA, Fungal
- RNA, Ribosomal
- RNA, Small Nuclear
- Saccharomyces cerevisiae